Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29208377 | 0.89 | CCNC (0.40) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL25425808 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL29587844 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL29587499 | 0.80 | KDM5A (0.45) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL25424837 | 0.80 | KDM5A (0.45) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL25426443 | 0.79 | ALDH1A1 (0.43) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL25424948 | 0.77 | ALDH1A1 (0.40) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL25423878 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL29208438 | 0.74 | LOXL2 (0.38) | KLKB1MAP4K1ADORA2A | |
| SCHEMBL25423945 | 0.72 | ALDH1A1 (0.46) | KDM4EALDH1A1HSD17B10TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204808-A1 | TARGET ENGAGEMENT ASSAY FOR RAS PROTEINS | Promega Corporation (US) | 2023-07-05 | — | — | EP | disclosed |