Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 10/20 | 0.39 |
| ▸ | PDE5A | O76074 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25424975 | 0.89 | PDE5A (0.41) | KIF11PDE5ALMNASTAT3SIRT1 | |
| SCHEMBL25423323 | 0.87 | KIF11 (0.40) | KIF11PDE5ALMNASTAT3NPSR1 | |
| SCHEMBL25426658 | 0.84 | PDE5A (0.43) | KIF11PDE5ALMNASTAT3SIRT1 | |
| SCHEMBL25423259 | 0.83 | PDE5A (0.45) | KIF11PDE5ALMNASTAT3SIRT1 | |
| SCHEMBL25423944 | 0.82 | PDE5A (0.41) | KIF11PDE5ALMNASTAT3SIRT1 | |
| SCHEMBL25424522 | 0.82 | PDE5A (0.43) | KIF11PDE5ALMNASTAT3SIRT1 | |
| SCHEMBL25425640 | 0.81 | PDE5A (0.43) | KIF11PDE5ALMNASTAT3SIRT1 | |
| SCHEMBL25423076 | 0.81 | PDE5A (0.42) | KIF11PDE5A | |
| SCHEMBL25425224 | 0.81 | PDE5A (0.43) | KIF11PDE5ALMNASTAT3HTR2A | |
| SCHEMBL25424470 | 0.79 | PDE5A (0.47) | KIF11PDE5ALMNASTAT3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130070-A2 | CARBOLINE COMPOUNDS AND USE THEREOF | PTC THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | claimed |