Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25426575 | 1.00 | HSD17B10 (0.34) | HSD17B10SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL25425430 | 0.90 | TLR2 (0.31) | HSD17B10FFAR2TLR2TLR1 | |
| SCHEMBL26999379 | 0.83 | CHRM2 (0.38) | HSD17B10SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL3635836 | 0.78 | HSD17B10 (0.38) | HSD17B10SMN1; SMN2 | |
| SCHEMBL28108703 | 0.76 | SMN1; SMN2 (0.33) | SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL26999367 | 0.73 | CHRM2 (0.36) | HSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL12797954 | 0.72 | CHRM2 (0.39) | HSD17B10SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL20819892 | 0.72 | FFAR2 (0.35) | FFAR2 | |
| SCHEMBL22444297 | 0.72 | FFAR2 (0.35) | FFAR2 | |
| SCHEMBL22371723 | 0.72 | FFAR2 (0.35) | FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4208452-A1 | QUINOLINE CGAS ANTAGONIST COMPOUNDS | Immunesensor Therapeutics, Inc. (US) | 2023-07-12 | — | — | EP | disclosed |