Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 4/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25425891 | 0.95 | TDP2 (0.46) | PARGTDP2TDP1KMT2ALMNA | |
| SCHEMBL25422095 | 0.92 | PARG (0.48) | PARGTDP2TDP1KMT2ACNR1 | |
| SCHEMBL25424268 | 0.91 | PARG (0.47) | PARGTDP2TDP1KMT2ACNR1 | |
| SCHEMBL25426667 | 0.85 | TDP2 (0.49) | PARGTDP2TDP1KMT2ALMNA | |
| SCHEMBL30478132 | 0.83 | HDAC1 (0.44) | PARGKMT2ALMNAMEN1MAPT | |
| SCHEMBL25426033 | 0.83 | HDAC1 (0.44) | PARGKMT2ALMNAMEN1MAPT | |
| SCHEMBL17434526 | 0.83 | PARG (0.59) | PARGKMT2ALMNAMEN1POLB | |
| SCHEMBL17434558 | 0.83 | CYP1A2 (0.60) | PARGKMT2ALMNAMEN1POLB | |
| SCHEMBL25425476 | 0.81 | F2RL3 (0.50) | PARGKMT2ALMNAMEN1PKM | |
| SCHEMBL25423174 | 0.79 | ALDH1A1 (0.45) | PARGKMT2ALMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452952-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) (IN) | 2024-10-30 | — | — | EP | disclosed |
| CN-118451062-A | Preparation and use of quinazolinediones | 科学与工业研究会(按照印度社会团体注册法案(1860年第21号法案)设立的注册机构) | 2024-08-06 | — | — | CN | disclosed |
| WO-2023119320-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2023-06-29 | — | — | WO | disclosed |