Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.41 |
| ▸ | NEK2 | P51955 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25425327 | 0.85 | HTR2A (0.43) | HTR2AHTR2CHTR2BCAMKK2NEK2 | |
| SCHEMBL25430167 | 0.77 | CAMKK2 (0.42) | HTR2AHTR2CHTR2BCAMKK2NEK2 | |
| SCHEMBL16319629 | 0.73 | CAMKK2 (0.50) | HTR2AHTR2CHTR2BCAMKK2NEK2 | |
| SCHEMBL25428211 | 0.73 | HTR2A (0.41) | HTR2AHTR2CHTR2BCAMKK2NEK2 | |
| SCHEMBL30509671 | 0.73 | HTR2A (0.41) | HTR2AHTR2CHTR2BCAMKK2NEK2 | |
| SCHEMBL21714635 | 0.72 | HTR2A (0.51) | HTR2AHTR2CHTR2BCAMKK2NEK2 | |
| SCHEMBL30509692 | 0.71 | HTR2A (0.49) | HTR2AHTR2CHTR2BLRRK2JAK3 | |
| SCHEMBL25865978 | 0.71 | HTR2A (0.49) | HTR2AHTR2CHTR2BLRRK2JAK3 | |
| SCHEMBL21714415 | 0.70 | DYRK1A (0.49) | HTR2AHTR2CHTR2BCAMKK2NEK2 | |
| SCHEMBL25427220 | 0.69 | HTR2A (0.42) | HTR2AHTR2CHTR2BCAMKK2NEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141225-A1 | FUSED HETEROCYCLES AS 5-HT2A RECEPTOR AGONISTS | ONSERO THERAPEUTICS INC. (US) | 2023-07-27 | — | — | WO | disclosed |