SCHEMBL254284

SCHEMBL254284

CC(C)c1ccc(Cl)cc1Cl

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.68
TP53 P04637 2/20 0.68
HTT P42858 1/20 0.68
GABRA1 P14867 1/20 0.44
GABRB1 P18505 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
IDO1 P14902 1/20 0.43
TDO2 P48775 1/20 0.43
TSHR P16473 3/20 0.42
CYP3A4 P08684 2/20 0.42
HSD17B10 Q99714 1/20 0.42
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
ALDH1A1 P00352 1/20 0.40
GAA P10253 1/20 0.40
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31045502 1.00 LMNA (0.68) LMNATP53HTTGABRA1GABRB1
SCHEMBL10973882 0.88 TP53 (0.55) LMNATP53HTTGABRA1GABRB1
SCHEMBL18097894 0.85 TP53 (0.68) LMNATP53HTTMEN1KMT2A
SCHEMBL30399939 0.83 TP53 (0.65) LMNATP53HTTMEN1KMT2A
SCHEMBL15053379 0.83 TP53 (0.65) LMNATP53HTTMEN1KMT2A
SCHEMBL5108877 0.83 TP53 (0.65) LMNATP53HTTMEN1KMT2A
SCHEMBL12197660 0.82 GABRA1 (0.52) LMNATP53HTTGABRA1GABRB1
SCHEMBL3899828 0.81 TP53 (1.00) LMNATP53HTTMEN1KMT2A
SCHEMBL13866426 0.81 TP53 (0.63) LMNATP53HTTMEN1KMT2A
SCHEMBL17069205 0.81 TP53 (0.63) LMNATP53HTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 665 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5030777-A Synthesis of 3,5-dichloroalkylbenzene and recovery of 1,3-dichlorobenzene STANDARD CHLORINE OF DELAWARE, INC. (US) 1991-07-09 US claimed
EP-0090875-B1 SEPARATION OF 3,5-DICHLOROCUMENE FROM A MIXTURE OF 3,5-DICHLOROCUMENE AND 2,4-DICHLOROCUMENE THE DOW CHEMICAL COMPANY (US) 1985-07-31 EP claimed
EP-0090875-A1 Separation of 3,5-dichlorocumene from a mixture of 3,5-dichlorocumene and 2,4-dichlorocumene THE DOW CHEMICAL COMPANY (US) 1983-10-12 EP claimed
US-4329524-A Separation of 3,5-dichlorocumene from a mixture of 3,5-dichlorocumene and 2,4-dichlorocumene THE DOW CHEMICAL COMPANY (US) 1982-05-11 US claimed
US-4104315-A Process for separating an ar, ar-dihalo-ar-alkylbenzene from an isomeric mixture of ar, ar-dihalo-ar-alkylbenzenes THE DOW CHEMICAL COMPANY (US) 1978-08-01 US claimed
JP-1319444-A None JP disclosed
US-12043613-B2 Inhibitors of SARM1 DISARM THERAPEUTICS, INC. (US) 2024-07-23 US disclosed
US-12043613-B2 Inhibitors of SARM1 DISARM THERAPEUTICS, INC. (US) 2024-07-23 US disclosed
US-12024507-B2 Compounds as GLP-1R agonists TERNS PHARMACEUTICALS, INC. (US) 2024-07-02 US disclosed
CN-118271338-A Organic compound, application thereof and organic electroluminescent device 北京绿人科技有限责任公司 2024-07-02 CN disclosed
CN-118108741-A Condensed ring compound, application thereof and organic electroluminescent device 北京绿人科技有限责任公司 2024-05-31 CN disclosed
WO-2024044493-A2 TREATMENT OF REPEAT EXPANSION DISEASE THE JOHNS HOPKINS UNIVERSITY (US) 2024-02-29 WO disclosed
US-4329524-A Separation of 3,5-dichlorocumene from a mixture of 3,5-dichlorocumene and 2,4-dichlorocumene THE DOW CHEMICAL COMPANY (US) 1982-05-11 US disclosed
US-4329524-A Separation of 3,5-dichlorocumene from a mixture of 3,5-dichlorocumene and 2,4-dichlorocumene THE DOW CHEMICAL COMPANY (US) 1982-05-11 US disclosed
US-4219570-A Insect repellents and a method of repelling insects AJINOMOTO COMPANY, INCORPORATED (JP) 1980-08-26 US disclosed
US-4104315-A Process for separating an ar, ar-dihalo-ar-alkylbenzene from an isomeric mixture of ar, ar-dihalo-ar-alkylbenzenes THE DOW CHEMICAL COMPANY (US) 1978-08-01 US disclosed
US-4104315-A Process for separating an ar, ar-dihalo-ar-alkylbenzene from an isomeric mixture of ar, ar-dihalo-ar-alkylbenzenes THE DOW CHEMICAL COMPANY (US) 1978-08-01 US disclosed
US-4087473-A Preferential aliphatic halogenation of ar-substituted alkylbenzenes THE DOW CHEMICAL COMPANY (US) 1978-05-02 US disclosed
US-4087473-A Preferential aliphatic halogenation of ar-substituted alkylbenzenes THE DOW CHEMICAL COMPANY (US) 1978-05-02 US disclosed
US-4059642-A Preferential alkylation or acylation of meta-disubstituted benzenes THE DOW CHEMICAL COMPANY (US) 1977-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12024507-B2 Compounds as GLP-1R agonists GLP1R, GIPR, GCGR LMNA 2472/4885TP53 3988/4885HTT 780/4885
US-12043613-B2 Inhibitors of SARM1 SARM1, SMN1; SMN2, SARNP LMNA 1340/4885TP53 2807/4885HTT 923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.