Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPKAPK3 | Q16644 | 2/20 | 0.35 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30544022 | 1.00 | TRPV1 (0.36) | TRPV1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL25341570 | 0.84 | CCNB2 (0.36) | TRPV1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL25430336 | 0.82 | CCNB2 (0.33) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL25428892 | 0.78 | TRPV1 (0.37) | TRPV1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL30544130 | 0.78 | TRPV1 (0.37) | TRPV1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL25430912 | 0.77 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL25341274 | 0.74 | KIF11 (0.50) | TRPV1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL25340553 | 0.74 | KIF11 (0.50) | TRPV1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL25973977 | 0.74 | TRPV1 (0.39) | TRPV1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL25974048 | 0.73 | TRPV1 (0.37) | TRPV1CCNB2CDK1CCNB1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |