Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.36 |
| ▸ | MAPKAPK3 | Q16644 | 2/20 | 0.36 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25428892 | 1.00 | TRPV1 (0.37) | TRPV1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL25427930 | 0.84 | PDE10A (0.45) | TRPV1PDE10A | |
| SCHEMBL30544141 | 0.84 | PDE10A (0.45) | TRPV1PDE10A | |
| SCHEMBL30544158 | 0.84 | CCNB2 (0.37) | TRPV1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL25340897 | 0.84 | CCNB2 (0.37) | TRPV1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL25428722 | 0.82 | TRPV1 (0.35) | TRPV1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL30544083 | 0.82 | TRPV1 (0.35) | TRPV1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL25428430 | 0.78 | TRPV1 (0.36) | TRPV1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL25430912 | 0.78 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL30544022 | 0.78 | TRPV1 (0.36) | TRPV1CCNB2CDK1CCNB1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |