Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.45 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.44 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 12/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 9/20 | 0.43 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30381702 | 1.00 | PDPK1 (0.45) | PDPK1TGFBR1IKBKETBK1DYRK1A | |
| SCHEMBL25858983 | 0.80 | CDK9 (0.67) | CDK9CCNT1 | |
| SCHEMBL31380019 | 0.80 | CDK9 (0.67) | CDK9CCNT1 | |
| SCHEMBL30381661 | 0.73 | PARP1 (0.44) | CDK9CCNT1PARP1 | |
| SCHEMBL25305073 | 0.73 | PARP1 (0.44) | CDK9CCNT1PARP1 | |
| SCHEMBL30769931 | 0.69 | PARP1 (0.41) | CDK9CCNT1PARP1 | |
| SCHEMBL27035288 | 0.69 | PARP1 (0.41) | CDK9CCNT1PARP1 | |
| SCHEMBL27058302 | 0.69 | PARP1 (0.44) | CDK9CCNT1PARP1 | |
| SCHEMBL27059126 | 0.68 | CCNT1 (0.43) | CDK9CCNT1PARP1 | |
| SCHEMBL30769916 | 0.68 | PARP1 (0.40) | CDK9CCNT1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107723-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023107723-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |