SCHEMBL30769931

SCHEMBL30769931

CN1CCC(c2nc3c(C4CCNCC4)ccnc3[nH]2)CC1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ PARP1 P09874 3/20 0.41
▸ CCNT1 O60563 5/20 0.39
▸ CDK9 P50750 5/20 0.39
▸ HTR1D P28221 4/20 0.38
▸ HTR1B P28222 4/20 0.38
▸ HTR1F P30939 4/20 0.38
▸ MAP3K12 Q12852 1/20 0.38
▸ ADORA2A P29274 1/20 0.36
▸ ADORA2B P29275 1/20 0.36
▸ HTR1A P08908 1/20 0.35
▸ HTR2A P28223 1/20 0.35
▸ HTR2B P41595 1/20 0.35
▸ HTR6 P50406 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27035288 1.00 PARP1 (0.41) PARP1CCNT1CDK9HTR1DHTR1B
SCHEMBL27058632 0.93 CDK9 (0.38) PARP1CCNT1CDK9HTR1DHTR1B
Hydrochloric Acid SCHEMBL30769764 0.92 CDK9 (0.37) PARP1CCNT1CDK9HTR1DHTR1B
SCHEMBL24683422 0.88 PARP1 (0.41) PARP1CCNT1CDK9HTR1AHTR6
SCHEMBL29845257 0.88 PARP1 (0.41) PARP1CCNT1CDK9HTR1AHTR6
SCHEMBL27058302 0.88 PARP1 (0.44) PARP1CCNT1CDK9HTR1DHTR1B
SCHEMBL27059126 0.87 CCNT1 (0.43) PARP1CCNT1CDK9HTR1DHTR1B
SCHEMBL30769916 0.86 PARP1 (0.40) PARP1CCNT1CDK9HTR1DHTR1B
SCHEMBL30769965 0.85 PARP1 (0.37) PARP1CDK9MAP3K12ADORA2AADORA2B
SCHEMBL30769759 0.84 IRAK4 (0.40) CCNT1CDK9MAP3K12HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022116-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF SANOFI-AVENTIS RECHERCHE & DÉVELOPPEMENT (FR) 2026-01-22 — — US disclosed
EP-4558500-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF Sanofi (FR) 2025-05-28 — — EP disclosed
WO-2024017977-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF SANOFI (FR) 2024-01-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022116-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF MAPK1, MAPK3, MAPK6 PARP1 2161/4885CCNT1 1488/4885CDK9 419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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