Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30544083 | 1.00 | TRPV1 (0.35) | TRPV1PDE10ANPC1CASP3RAB9A | |
| SCHEMBL30544132 | 0.85 | FEN1 (0.41) | TRPV1PDE10A | |
| SCHEMBL25429318 | 0.85 | FEN1 (0.41) | TRPV1PDE10A | |
| SCHEMBL30544130 | 0.82 | TRPV1 (0.37) | TRPV1PDE10ACCNB2CDK1CCNB1 | |
| SCHEMBL25428892 | 0.82 | TRPV1 (0.37) | TRPV1PDE10ACCNB2CDK1CCNB1 | |
| SCHEMBL30544158 | 0.82 | CCNB2 (0.37) | TRPV1PDE10ACCNB2CDK1CCNB1 | |
| SCHEMBL25340897 | 0.82 | CCNB2 (0.37) | TRPV1PDE10ACCNB2CDK1CCNB1 | |
| SCHEMBL25951852 | 0.79 | TRPV1 (0.41) | TRPV1RAB9ATRPA1 | |
| SCHEMBL25430336 | 0.79 | CCNB2 (0.33) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL25973903 | 0.78 | NPC1 (0.39) | TRPV1NPC1CASP3RAB9ASENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |