Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25375442 | 0.87 | FEN1 (0.38) | RAB9AP2RY1 | |
| SCHEMBL25973972 | 0.87 | TRPV1 (0.39) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL25975148 | 0.84 | NPC1 (0.36) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL30519311 | 0.82 | SLC6A2 (0.36) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL25341461 | 0.82 | SLC6A2 (0.36) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL25974745 | 0.82 | KIF11 (0.51) | NPC1RAB9AALDH1A1MAPTATM | |
| SCHEMBL25340813 | 0.82 | KCNH2 (0.38) | RAB9ATRPV1MAPTATM | |
| SCHEMBL25343367 | 0.82 | FEN1 (0.47) | COMTALDH1A1MAPTATM | |
| SCHEMBL30519411 | 0.82 | KCNH2 (0.38) | RAB9ATRPV1MAPTATM | |
| SCHEMBL25378801 | 0.81 | FEN1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |