SCHEMBL25429

SCHEMBL25429

CC(C(=O)O)C(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O

nearest known ligand 0.86

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NAA50 Q9GZZ1 2/20 0.86
▸ CHAT P28329 2/20 0.82
▸ EP300 Q09472 2/20 0.81
▸ AURKA O14965 2/20 0.81
▸ KAT2B Q92831 1/20 0.81
▸ KAT5 Q92993 1/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29457604 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT2B
SCHEMBL28671996 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT2B
SCHEMBL29378271 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT2B
SCHEMBL17997995 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT2B
SCHEMBL12934617 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT2B
SCHEMBL4286414 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT2B
SCHEMBL30582704 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT2B
SCHEMBL187858 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT2B
SCHEMBL188315 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT2B
SCHEMBL30074506 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2425 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116262912-B Hydroxylase mutant and application thereof Center for excellence and innovation in molecular plant science, Chinese Academy of Sciences (CN) 2026-05-26 — — CN claimed
US-20260125432-A1 MALTOSE DEPENDENT DEGRONS, MALTOSE-RESPONSIVE PROMOTERS, STABILIZATION CONSTRUCTS, AND THEIR USE IN PRODUCTION OF NON-CATABOLIC COMPOUNDS AMYRIS INC (US) 2026-05-07 — — US claimed
EP-4713320-A2 BCAT2 INHIBITORS Agios Pharmaceuticals, Inc. (US) 2026-03-25 — — EP claimed
US-12577591-B2 Microorganisms and methods for increasing co-factors GENOMATICA, INC. (US) 2026-03-17 — — US claimed
US-20260021186-A1 Fatty Acid-D-Amino Acid Peptides Conjugates as Anaplerotic Compounds for Use in Treating Propionic Acidemia, Methylmalonic Acidurias, and Energy Metabolic Disorders UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) 2026-01-22 — — US claimed
US-12516388-B2 Biosensors for polyketide extender units and uses thereof NORTH CAROLINA STATE UNIVERSITY (US) 2026-01-06 — — US claimed
US-20250250214-A1 METHOD FOR DEHYDRATION OF ALCOHOL MIXTURES BRASKEM S.A. (BR) 2025-08-07 — — US claimed
EP-3957736-B1 PRODUCTION OF ODD CHAIN FATTY ACID DERIVATIVES IN RECOMBINANT MICROBIAL CELLS GENOMATICA INC (US) 2025-08-06 — — EP claimed
EP-4565325-A2 FATTY ACID-D-AMINO ACID PEPTIDES CONJUGATES AS ANAPLEROTIC COMPOUNDS FOR USE IN TREATING PROPIONIC ACIDEMIA, METHYLMALONIC ACIDURIAS, AND ENERGY METABOLIC DISORDERS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2025-06-11 — — EP claimed
EP-4565706-A1 MICROBIAL PRODUCTION OF MONOMERS FOR RECYCLING OF PLASTIC POLYMERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-06-11 — — EP claimed
US-20040014183-A1 Secondary metabolite congener distribution modulation KOSAN BIOSCIENCES, INC. 2004-01-22 — — US claimed
US-20030225006-A1 Novel spinosyn-producing polyketide synthases BURNS LESLEY S 2003-12-04 — — US claimed
WO-2003072730-A2 SECONDARY METABOLITE CONGENER DISTRIBUTION MODULATION KOSAN BIOSCIENCES, INC. (US) 2003-09-04 — — WO claimed
WO-2003070908-A2 NOVEL SPINOSYN-PRODUCING POLYKETIDE SYNTHASES DOW AGROSCIENCES LLC (US) 2003-08-28 — — WO claimed
EP-1309695-A2 POLYKETIDES AND THEIR SYNTHESIS Biotica Technology Limited (GB) 2003-05-14 — — EP claimed
US-6448476-B1 LOCALIZED IN CHLOROPLASTS OR PLATIDS TO CONFER HERBICIDE RESISTANCE AGAINST AMPA (AMINOMETHYLPHOSPHORIC ACID) HERBICIDES TO CROP PLANTS MONSANTO TECHNOLOGY LLC 2002-09-10 — — US claimed
WO-2002014482-A2 POLYKETIDES AND THEIR SYNTHESIS BIOTICA TECHNOLOGY LIMITED (GB) 2002-02-21 — — WO claimed
CN-1333835-A Phosphonate metabolizing plants MONSANTO CO (US) 2002-01-30 — — CN claimed
EP-1098630-A2 COMPOSITION FOR ENHANCING EPIDERMAL LIPID PRODUCTION Biomed Research and Technologies, Inc. (US) 2001-05-16 — — EP claimed
WO-2000004870-A2 COMPOSITION FOR ENHANCING EPIDERMAL LIPID PRODUCTION BIOMED RESEARCH AND TECHNOLOGIES, INC. (US) 2000-02-03 — — WO claimed
Send feedback