Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAA50 | Q9GZZ1 | 2/20 | 0.86 |
| ▸ | CHAT | P28329 | 2/20 | 0.82 |
| ▸ | EP300 | Q09472 | 2/20 | 0.81 |
| ▸ | AURKA | O14965 | 2/20 | 0.81 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.81 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29457604 | 1.00 | NAA50 (0.86) | NAA50CHATEP300AURKAKAT2B | |
| SCHEMBL28671996 | 1.00 | NAA50 (0.86) | NAA50CHATEP300AURKAKAT2B | |
| SCHEMBL29378271 | 1.00 | NAA50 (0.86) | NAA50CHATEP300AURKAKAT2B | |
| SCHEMBL17997995 | 1.00 | NAA50 (0.86) | NAA50CHATEP300AURKAKAT2B | |
| SCHEMBL12934617 | 1.00 | NAA50 (0.86) | NAA50CHATEP300AURKAKAT2B | |
| SCHEMBL30582704 | 1.00 | NAA50 (0.86) | NAA50CHATEP300AURKAKAT2B | |
| SCHEMBL187858 | 1.00 | NAA50 (0.86) | NAA50CHATEP300AURKAKAT2B | |
| SCHEMBL188315 | 1.00 | NAA50 (0.86) | NAA50CHATEP300AURKAKAT2B | |
| SCHEMBL25429 | 1.00 | NAA50 (0.86) | NAA50CHATEP300AURKAKAT2B | |
| SCHEMBL30074506 | 1.00 | NAA50 (0.86) | NAA50CHATEP300AURKAKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090098615-A1 | GENETICALLY MODIFIED CELLS AND METHODS FOR CONVERTING (R)-METHYLMALONYL COA TO (S)-METHYLMALONYL COA | KOSAN BIOSCIENCES, INC. | 2009-04-16 | — | — | US | disclosed |
| US-7291486-B2 | Genetically modified cells and methods for converting (R)-methylmalonyl CoA to (S)-methylmalonyl CoA | KOSAN BIOSCIENCES, INC. (US) | 2007-11-06 | — | — | US | disclosed |
| EP-1224300-B9 | HETEROLOGOUS PRODUCTION OF POLYKETIDES | KOSAN BIOSCIENCES INC (US) | 2007-09-26 | — | — | EP | disclosed |
| EP-1224300-B1 | HETEROLOGOUS PRODUCTION OF POLYKETIDES | KOSAN BIOSCIENCES INC (US) | 2007-03-07 | — | — | EP | disclosed |
| US-7011959-B1 | Heterologous production of polyketides | KOSAN BIOSCIENCES, INC. (US) | 2006-03-14 | — | — | US | disclosed |
| US-20040185541-A1 | Heterologous production of polyketides | BIOTICA TECHNOLOGY LIMITED (GB) | 2004-09-23 | — | — | US | disclosed |
| US-20040005672-A1 | Heterologous production of polyketides | KOSAN BIOSCIENCES, INC. | 2004-01-08 | — | — | US | disclosed |
| US-20020142401-A1 | Isolated gene for methylmalonyl CoA epimerase and uses thereof | SANTI DANIEL (US) | 2002-10-03 | — | — | US | disclosed |
| EP-1224300-A2 | HETEROLOGOUS PRODUCTION OF POLYKETIDES | Kosan Biosciences, Inc. (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001031035-A2 | HETEROLOGOUS PRODUCTION OF POLYKETIDES | KOSAN BIOSCIENCES, INC. (US) | 2001-05-03 | — | — | WO | disclosed |