Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.43 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.43 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27889608 | 0.83 | TRPV1 (0.44) | SKP2TRPV1METAP2PSMB5HSD11B1 | |
| SCHEMBL2542906 | 0.83 | HPGD (0.46) | GAASKP2MEN1KMT2AMAPT | |
| SCHEMBL15854826 | 0.82 | RAPGEF4 (0.53) | SKP2TRPV1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1031878 | 0.81 | KMT2A (0.49) | GAASKP2TRPV1MEN1KMT2A | |
| SCHEMBL16542333 | 0.79 | HPGD (0.43) | GAASKP2MEN1KMT2AMAPT | |
| SCHEMBL23092997 | 0.78 | SKP2 (0.58) | SKP2METAP2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2539187 | 0.78 | TRPV1 (0.58) | GAATRPV1MEN1KMT2AHSD11B1 | |
| SCHEMBL23432180 | 0.78 | PSMB5 (0.51) | GAATRPV1METAP2MEN1KMT2A | |
| SCHEMBL13316758 | 0.77 | METAP2 (0.44) | GAASKP2METAP2CYP3A4CYP2D6 | |
| SCHEMBL22446985 | 0.77 | MAPT (0.52) | GAATRPV1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1850185-B1 | Imaging member, method of imaging using it and method of making said imaging member | XEROX CORP (US) | 2011-01-19 | — | — | EP | disclosed |
| US-20070254226-A1 | Imaging member | XEROX CORPORATION | 2007-11-01 | — | — | US | disclosed |
| EP-1850185-A2 | Imaging Member | Xerox Corporation (US) | 2007-10-31 | — | — | EP | disclosed |