Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12393616 | 0.98 | KEAP1 (0.37) | KEAP1NFE2L2HSD11B1ALDH1A1NAAA | |
| SCHEMBL5686257 | 0.90 | KEAP1 (0.33) | KEAP1NFE2L2ALDH1A1RECQLEPHX1 | |
| SCHEMBL11522217 | 0.89 | MEN1 (0.35) | HSD11B1ALDH1A1MEN1KMT2A | |
| SCHEMBL11453750 | 0.88 | CYP2D6 (0.34) | KEAP1NFE2L2ALDH1A1NAAARECQL | |
| SCHEMBL29169850 | 0.88 | CHRM2 (0.35) | KEAP1NFE2L2ALDH1A1NAAARECQL | |
| SCHEMBL8784444 | 0.85 | KEAP1 (0.31) | KEAP1NFE2L2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4870836 | 0.85 | CYP1A2 (0.38) | NAAAEPHX1 | |
| SCHEMBL27494291 | 0.85 | MEN1 (0.33) | KEAP1NFE2L2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL17747242 | 0.81 | SHBG (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL5197125 | 0.81 | EPHX1 (0.38) | HSD11B1ALDH1A1RECQLEPHX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023148277-A1 | AGENTS AND METHODS FOR TARGETED DELIVERY OF NUCLEIC ACIDS TO CELLS | BioNTech SE (DE) | 2023-08-10 | — | — | WO | disclosed |