Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16723452 | 0.90 | MAPT (0.43) | ALDH1A1KMT2ALMNAMEN1GAA | |
| SCHEMBL1292014 | 0.89 | ALDH1A1 (0.48) | ALDH1A1KMT2ALMNAMEN1FKBP1A | |
| SCHEMBL7664737 | 0.86 | ALDH1A1 (0.45) | ALDH1A1KMT2ALMNAMEN1POLB | |
| SCHEMBL2570325 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KMT2ALMNAMEN1POLB | |
| SCHEMBL26159159 | 0.83 | KMT2A (0.50) | ALDH1A1KMT2ALMNAMEN1FKBP1A | |
| SCHEMBL22578028 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KMT2ALMNAMEN1FKBP1A | |
| SCHEMBL10223586 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KMT2ALMNAMEN1POLB | |
| SCHEMBL16628426 | 0.77 | TP53 (0.45) | KMT2ALMNAMEN1POLBGAA | |
| SCHEMBL17158242 | 0.76 | KCNN4 (0.50) | ALDH1A1KMT2ALMNAMEN1POLB | |
| SCHEMBL2702360 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |