Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380201 | 0.89 | EPHX2 (0.45) | ALDH1A1EPHX2EPHX1KMT2ALMNA | |
| SCHEMBL25429745 | 0.86 | ALDH1A1 (0.48) | ALDH1A1KMT2ALMNAPKML3MBTL1 | |
| SCHEMBL1292014 | 0.84 | ALDH1A1 (0.48) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL2570325 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KMT2ALMNAPKML3MBTL1 | |
| SCHEMBL22578028 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KMT2ALMNAPKMMEN1 | |
| SCHEMBL26159159 | 0.79 | KMT2A (0.50) | ALDH1A1KMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL16723452 | 0.77 | MAPT (0.43) | ALDH1A1KMT2ALMNAMEN1GAA | |
| SCHEMBL7383036 | 0.75 | CYP11B1 (0.49) | KMT2ALMNAMEN1POLB | |
| SCHEMBL10223586 | 0.73 | ALDH1A1 (0.48) | ALDH1A1KMT2ALMNAPKML3MBTL1 | |
| SCHEMBL17158242 | 0.72 | KCNN4 (0.50) | ALDH1A1KMT2ALMNAMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369221-B1 | Thiazolobenzoheterocycles, preparation and medicines containing same | AVENTIS PHARMA S.A. (FR) | 2002-04-09 | — | — | US | disclosed |