Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38656583 | 1.00 | MAPK1 (0.57) | MAPK1HIF1AKDM4EL3MBTL1DYRK1A | |
| Hydrochloric Acid SCHEMBL6345836 | 0.98 | MAPK1 (0.56) | MAPK1HIF1AKDM4EL3MBTL1DYRK1A | |
| SCHEMBL38656189 | 0.87 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1DYRK1AGPR119 | |
| SCHEMBL721291 | 0.86 | MAPK1 (0.65) | MAPK1KDM4EL3MBTL1DYRK1AHPGD | |
| SCHEMBL31359497 | 0.86 | MAPK1 (0.65) | MAPK1KDM4EL3MBTL1DYRK1AHPGD | |
| SCHEMBL7942053 | 0.86 | MAPK1 (0.53) | MAPK1HIF1AKDM4EL3MBTL1DYRK1A | |
| SCHEMBL2037294 | 0.85 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1DYRK1AGPR119 | |
| SCHEMBL11041168 | 0.85 | MAPK1 (0.59) | MAPK1HIF1AKDM4EL3MBTL1DYRK1A | |
| Hydrochloric Acid SCHEMBL14125808 | 0.84 | MAPK1 (0.62) | MAPK1KDM4EL3MBTL1DYRK1AHPGD | |
| SCHEMBL5937430 | 0.83 | EGLN1 (0.57) | MAPK1KDM4EL3MBTL1DYRK1ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612368-B2 | Cancer treatments targeting cancer stem cells | REMEDY PLAN, INC. (US) | 2026-04-28 | — | — | US | disclosed |
| CN-119930509-A | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-114929672-B | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2025-01-21 | — | — | CN | disclosed |
| US-20230023124-A1 | CANCER TREATMENTS TARGETING CANCER STEM CELLS | REMEDY PLAN, INC. (US) | 2023-01-26 | — | — | US | disclosed |
| US-20230023124-A1 | CANCER TREATMENTS TARGETING CANCER STEM CELLS | REMEDY PLAN, INC. (US) | 2023-01-26 | — | — | US | disclosed |
| EP-4055008-A1 | CANCER TREATMENTS TARGETING CANCER STEM CELLS | Remedy Plan, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |
| CN-114929672-A | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| WO-2012031298-A2 | ETHYNYLBENZENE DERIVATIVES | DUKE UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12612368-B2 | Cancer treatments targeting cancer stem cells | MALT1, BCOR, MCL1 | MAPK1 2918/4885HIF1A 177/4885KDM4E 2964/4885 |
| US-20230023124-A1 | CANCER TREATMENTS TARGETING CANCER STEM CELLS | MCL1, KIT, GLI1 | MAPK1 3430/4885HIF1A 366/4885KDM4E 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.