SCHEMBL38656189

SCHEMBL38656189

COC(=O)c1ccc(-c2ccc(N)nc2)cn1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.57
MKNK1 Q9BUB5 1/20 0.51
MKNK2 Q9HBH9 1/20 0.51
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 1/20 0.49
GAA P10253 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.46
DYRK1A Q13627 1/20 0.46
PIK3CD O00329 1/20 0.44
CYP3A4 P08684 1/20 0.42
PIK3CA P42336 1/20 0.42
MTOR P42345 2/20 0.42
LTA4H P09960 1/20 0.41
HPGD P15428 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
MAP4K4 O95819 1/20 0.41
GPR119 Q8TDV5 1/20 0.41
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL254303 0.87 MAPK1 (0.57) MAPK1MKNK1MKNK2KDM4EALDH1A1
SCHEMBL38656583 0.87 MAPK1 (0.57) MAPK1MKNK1MKNK2KDM4EALDH1A1
Hydrochloric Acid SCHEMBL6345836 0.85 MAPK1 (0.56) MAPK1MKNK1MKNK2KDM4EALDH1A1
SCHEMBL5543060 0.83 MKNK1 (0.65) MAPK1MKNK1MKNK2KDM4EALDH1A1
SCHEMBL31188315 0.83 MKNK1 (0.47) MAPK1MKNK1MKNK2KDM4EALDH1A1
SCHEMBL2037294 0.81 MAPK1 (0.59) MAPK1KDM4EL3MBTL1DYRK1AHPGD
SCHEMBL11041168 0.81 MAPK1 (0.59) MAPK1KDM4EL3MBTL1DYRK1A
SCHEMBL5937430 0.80 EGLN1 (0.57) MAPK1KDM4EALDH1A1L3MBTL1DYRK1A
SCHEMBL7942053 0.80 MAPK1 (0.53) MAPK1KDM4EGAAL3MBTL1DYRK1A
SCHEMBL31073082 0.79 TRPC6 (0.54) MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102082-A1 ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use GIPR, MC2R, GRPR MAPK1 4489/4885MKNK1 4361/4885MKNK2 4069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.