Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | GABRE | P78334 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041168 | 0.86 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1DYRK1AMEN1 | |
| SCHEMBL31463324 | 0.85 | MAPK1 (0.67) | MAPK1CA12CA1CA2CA7 | |
| SCHEMBL31463327 | 0.85 | MAPK1 (0.67) | MAPK1CA12CA1CA2CA7 | |
| SCHEMBL164488 | 0.85 | MAPK1 (0.67) | MAPK1CA12CA1CA2CA7 | |
| SCHEMBL254303 | 0.85 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1DYRK1AMEN1 | |
| SCHEMBL5937430 | 0.85 | EGLN1 (0.57) | MAPK1KDM4EL3MBTL1DYRK1ANPC1 | |
| SCHEMBL38656583 | 0.85 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1DYRK1AMEN1 | |
| SCHEMBL1178942 | 0.85 | FTO (0.58) | MAPK1GABRPGABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL1585177 | 0.84 | MAPK1 (0.65) | MAPK1CA12CA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL6345836 | 0.83 | MAPK1 (0.56) | MAPK1KDM4EL3MBTL1DYRK1ALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150175644-A1 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | UNIV BASEL (CH) | 2015-06-25 | — | — | US | disclosed |
| EP-2604619-A2 | Mannose derivatives as antagonists of bacterial adhesion | University of Basel (CH) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012164074-A1 | MANNOSE PHOSPHATE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | UNIVERSITY OF BASEL (CH) | 2012-12-06 | — | — | WO | disclosed |
| US-20120270824-A1 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | UNIVERSITY OF BASEL (CH) | 2012-10-25 | — | — | US | disclosed |
| EP-2513128-A2 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | University of Basel (CH) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011073112-A2 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | UNIVERSITY OF BASEL (CH) | 2011-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270824-A1 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | MAN2A1, MANBA, M6PR | MAPK1 523/4885CA12 4430/4885CA1 4756/4885 |
| US-20150175644-A1 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | MAN2A1, MANBA, M6PR | MAPK1 523/4885CA12 4430/4885CA1 4756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.