Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25429117 | 0.83 | HSD17B10 (0.55) | EPHX2TP53MAPTAKR1C3ALDH1A1 | |
| SCHEMBL25972998 | 0.70 | EPHX2 (0.43) | EPHX2TP53MAPTAKR1C3MEN1 | |
| SCHEMBL16481432 | 0.70 | KIF11 (0.52) | TP53MAPTAKR1C3MEN1ALDH1A1 | |
| SCHEMBL30544095 | 0.70 | EPHX2 (0.47) | EPHX2TP53MAPTAKR1C3TRPV1 | |
| SCHEMBL25429357 | 0.70 | TP53 (0.42) | EPHX2TP53MAPTAKR1C3TRPV1 | |
| SCHEMBL25340011 | 0.70 | EPHX2 (0.47) | EPHX2TP53MAPTAKR1C3TRPV1 | |
| SCHEMBL25973157 | 0.69 | NTRK1 (0.50) | EPHX2TP53MAPTAKR1C3MEN1 | |
| SCHEMBL25377311 | 0.69 | S1PR1 (0.45) | EPHX2 | |
| SCHEMBL30519396 | 0.69 | KIF11 (0.62) | EPHX2TP53MAPTAKR1C3MEN1 | |
| SCHEMBL25430825 | 0.69 | TP53 (0.45) | EPHX2TP53MAPTAKR1C3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |