Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16481432 | 0.81 | KIF11 (0.52) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL25974055 | 0.79 | EPHX2 (0.46) | EPHX2MEN1KMT2AALDH1A1 | |
| SCHEMBL25973157 | 0.79 | NTRK1 (0.50) | EPHX2NTRK1MAPTMEN1KMT2A | |
| SCHEMBL25430825 | 0.78 | TP53 (0.45) | EPHX2NTRK1MAPTMEN1KMT2A | |
| SCHEMBL25377311 | 0.76 | S1PR1 (0.45) | EPHX2TAS2R14 | |
| SCHEMBL30519396 | 0.75 | KIF11 (0.62) | EPHX2NTRK1MAPTMEN1KMT2A | |
| SCHEMBL25977555 | 0.75 | KIF11 (0.53) | EPHX2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL25977664 | 0.75 | KIF11 (0.62) | EPHX2NTRK1MAPTMEN1KMT2A | |
| SCHEMBL16481038 | 0.75 | MEN1 (0.49) | EPHX2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1921457 | 0.75 | ALDH1A1 (0.55) | EPHX2MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |