Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | METAP2 | P50579 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.37 |
| ▸ | UGT2B17 | O75795 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4862036 | 0.72 | KMT2A (0.39) | NR3C1SLC6A3LMNACYP3A4TSHR | |
| SCHEMBL29038905 | 0.66 | ATM (0.42) | LMNA | |
| SCHEMBL4754008 | 0.62 | MAPT (0.61) | L3MBTL1LMNA | |
| SCHEMBL3487513 | 0.62 | MAPT (0.61) | L3MBTL1LMNA | |
| SCHEMBL7055028 | 0.62 | MAPT (0.61) | L3MBTL1LMNA | |
| SCHEMBL7053572 | 0.62 | MAPT (0.61) | L3MBTL1LMNA | |
| SCHEMBL4754009 | 0.62 | MAPT (0.61) | L3MBTL1LMNA | |
| SCHEMBL14292320 | 0.62 | MAPT (0.61) | L3MBTL1LMNA | |
| SCHEMBL4558510 | 0.62 | OPRL1 (0.39) | SLC6A3LMNACYP3A4SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL2710013 | 0.62 | MAOB (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147531-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-08-03 | — | — | WO | disclosed |