Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 0.35 |
| ▸ | PRKCB | P05771 | 6/20 | 0.35 |
| ▸ | PRKCA | P17252 | 3/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25431565 | 0.89 | GSK3B (0.39) | GSK3BPRKCBPRKCAPRKCGPDE10A | |
| SCHEMBL25430613 | 0.83 | TEK (0.35) | PDE10A | |
| SCHEMBL25428812 | 0.83 | PDE10A (0.38) | PDE10A | |
| SCHEMBL25374074 | 0.75 | PDE10A (0.44) | GSK3BPRKCBPDE10A | |
| SCHEMBL25432124 | 0.73 | ELANE (0.40) | PDE10AAURKBELANEAURKATPX2 | |
| SCHEMBL25952586 | 0.73 | PDE10A (0.34) | GSK3BPRKCBPRKCAPDE10A | |
| SCHEMBL25428450 | 0.71 | SCN9A (0.42) | GSK3BPRKCBPDE10ACCNB2CDK1 | |
| SCHEMBL30544047 | 0.71 | SCN9A (0.42) | GSK3BPRKCBPDE10ACCNB2CDK1 | |
| SCHEMBL25377299 | 0.69 | PDE10A (0.46) | PDE10A | |
| SCHEMBL25377875 | 0.66 | PDE10A (0.44) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |