Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25428450 | 0.89 | SCN9A (0.42) | PDE10ASCN9AMETAP2 | |
| SCHEMBL30544047 | 0.89 | SCN9A (0.42) | PDE10ASCN9AMETAP2 | |
| SCHEMBL25952586 | 0.88 | PDE10A (0.34) | PDE10AFEN1 | |
| SCHEMBL25430936 | 0.83 | GSK3B (0.35) | PDE10A | |
| SCHEMBL25374074 | 0.81 | PDE10A (0.44) | PDE10A | |
| SCHEMBL25430296 | 0.77 | PDE10A (0.41) | PDE10ASCN9AFEN1 | |
| SCHEMBL25433941 | 0.76 | PDE10A (0.35) | PDE10ASCN9A | |
| SCHEMBL25427800 | 0.75 | SCN9A (0.39) | PDE10ASCN9AFEN1METAP2 | |
| SCHEMBL30544057 | 0.75 | SCN9A (0.44) | SCN9AFFAR4 | |
| SCHEMBL25952320 | 0.75 | SCN9A (0.44) | SCN9AFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |