Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.42 |
| ▸ | FEN1 | P39748 | 3/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31208015 | 1.00 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGTRPV3 | |
| SCHEMBL25430422 | 0.85 | PDE4B (0.46) | TRPV3PDE4BALOX5APFEN1HPGDS | |
| SCHEMBL31208008 | 0.85 | PDE4B (0.46) | TRPV3PDE4BALOX5APFEN1HPGDS | |
| SCHEMBL19404832 | 0.76 | TRPV3 (0.52) | TRPV3PDE4BALOX5APFEN1HPGDS | |
| SCHEMBL25430899 | 0.76 | GRM1 (0.38) | CCNT1CDK9GPR119 | |
| SCHEMBL31208006 | 0.76 | GRM1 (0.38) | CCNT1CDK9GPR119 | |
| SCHEMBL19404833 | 0.75 | SMN1; SMN2 (0.50) | TRPV3PDE4BHPGDSKDM4EGPR119 | |
| SCHEMBL25432160 | 0.75 | PDE4B (0.46) | PIK3CDTRPV3PDE4BHPGDSKDM4E | |
| SCHEMBL31208014 | 0.75 | PDE4B (0.46) | PIK3CDTRPV3PDE4BHPGDSKDM4E | |
| SCHEMBL4744810 | 0.75 | PDPK1 (0.46) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4674841-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2026-01-07 | — | — | EP | disclosed |
| EP-4444305-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |