Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.45 |
| ▸ | CDK9 | P50750 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31208008 | 1.00 | PDE4B (0.46) | PDE4BTRPV3BRD3CCNT1CDK9 | |
| SCHEMBL25431429 | 0.85 | PIK3CD (0.43) | PDE4BTRPV3CCNT1CDK9HTT | |
| SCHEMBL31208015 | 0.85 | PIK3CD (0.43) | PDE4BTRPV3CCNT1CDK9HTT | |
| SCHEMBL25366217 | 0.77 | TRPV3 (0.52) | PDE4BTRPV3HTTKDM4EALDH1A1 | |
| SCHEMBL31208026 | 0.77 | TRPV3 (0.52) | PDE4BTRPV3HTTKDM4EALDH1A1 | |
| SCHEMBL26025833 | 0.77 | TRPV3 (0.52) | PDE4BTRPV3HTTKDM4EALDH1A1 | |
| SCHEMBL25361679 | 0.77 | TRPV3 (0.50) | PDE4BTRPV3HTTKDM4EALDH1A1 | |
| SCHEMBL25361414 | 0.77 | TRPV3 (0.50) | PDE4BTRPV3HTTKDM4EALDH1A1 | |
| SCHEMBL30496025 | 0.77 | TRPV3 (0.50) | PDE4BTRPV3HTTKDM4EALDH1A1 | |
| SCHEMBL19405079 | 0.77 | TRPV3 (0.49) | PDE4BTRPV3CCNT1CDK9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4674841-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2026-01-07 | — | — | EP | disclosed |
| EP-4444305-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |