Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 7/20 | 0.43 |
| ▸ | GRM5 | P41594 | 6/20 | 0.43 |
| ▸ | CDK9 | P50750 | 9/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31208020 | 1.00 | GRM1 (0.43) | GRM1GRM5CDK9CCNT1PDK4 | |
| SCHEMBL31208006 | 0.84 | GRM1 (0.38) | GRM1GRM5CDK9CCNT1 | |
| SCHEMBL25430899 | 0.84 | GRM1 (0.38) | GRM1GRM5CDK9CCNT1 | |
| SCHEMBL25362816 | 0.77 | GRM1 (0.41) | GRM1GRM5PDK4 | |
| SCHEMBL30496081 | 0.77 | GRM1 (0.41) | GRM1GRM5PDK4 | |
| SCHEMBL29899495 | 0.76 | GRM1 (0.43) | GRM1GRM5CDK9CCNT1PDK4 | |
| SCHEMBL25432299 | 0.76 | CYP11B2 (0.40) | GRM1GRM5PDK4JAK1 | |
| SCHEMBL31208023 | 0.76 | CYP11B2 (0.40) | GRM1GRM5PDK4JAK1 | |
| SCHEMBL25430422 | 0.75 | PDE4B (0.46) | CDK9CCNT1 | |
| SCHEMBL31208008 | 0.75 | PDE4B (0.46) | CDK9CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4674841-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2026-01-07 | — | — | EP | disclosed |
| EP-4444305-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |