Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MAP2 | P11137 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30590427 | 1.00 | CSF1R (0.48) | CSF1RCYP1A2MEN1ALDH1A1CYP3A4 | |
| SCHEMBL30044896 | 0.80 | CSF1R (0.49) | CSF1RCYP1A2GSK3BMAP2GRIN2D | |
| SCHEMBL23498272 | 0.80 | CSF1R (0.49) | CSF1RCYP1A2GSK3BMAP2GRIN2D | |
| SCHEMBL31139832 | 0.79 | SIRT1 (0.52) | CSF1RCYP1A2GSK3BMAP2GRIN2D | |
| SCHEMBL25430492 | 0.79 | SIRT1 (0.52) | CSF1RCYP1A2GSK3BMAP2GRIN2D | |
| SCHEMBL23510959 | 0.79 | GRIN2D (0.58) | CSF1RCYP1A2MEN1ALDH1A1CYP3A4 | |
| SCHEMBL25432139 | 0.77 | PADI4 (0.56) | ALDH1A1LMNA | |
| SCHEMBL25432141 | 0.77 | PADI4 (0.56) | ALDH1A1LMNA | |
| SCHEMBL30043560 | 0.74 | MAP2 (0.74) | CSF1RCYP1A2ALDH1A1GSK3BMAP2 | |
| SCHEMBL6059495 | 0.74 | MAP2 (0.74) | CSF1RCYP1A2ALDH1A1GSK3BMAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023161782-A1 | NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS | SATYARX PHARMA INNOVATIONS PVT LTD (IN) | 2023-08-31 | — | — | WO | disclosed |