Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | MAP2 | P11137 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23498272 | 1.00 | CSF1R (0.49) | CSF1RMAP2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL25430492 | 0.86 | SIRT1 (0.52) | CSF1RMAP2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL31139832 | 0.86 | SIRT1 (0.52) | CSF1RMAP2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL23510959 | 0.86 | GRIN2D (0.58) | CSF1RGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30043560 | 0.80 | MAP2 (0.74) | CSF1RMAP2KDM4ECYP1A2HPGD | |
| SCHEMBL6059495 | 0.80 | MAP2 (0.74) | CSF1RMAP2KDM4ECYP1A2HPGD | |
| SCHEMBL25432829 | 0.80 | CSF1R (0.48) | CSF1RMAP2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL30590427 | 0.80 | CSF1R (0.48) | CSF1RMAP2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL19863777 | 0.79 | CSF1R (0.60) | CSF1RMAP2KDM4EGSK3B | |
| SCHEMBL22450909 | 0.79 | MAP2 (0.52) | MAP2LMNACYP1A2GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4073054-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF TUMORS | Fondazione Istituto Italiano di Tecnologia (IT) | 2022-10-19 | — | — | EP | disclosed |