Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL25432965

O=C(NCC1CCNC1)C1CCN(c2nc(-c3ccc(Cl)cc3)no2)CC1.O=C(O)C(F)(F)F

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.50
▸ LMNA P02545 2/20 0.46
▸ POLB P06746 1/20 0.43
▸ MEN1 O00255 3/20 0.42
▸ KMT2A Q03164 3/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25401980 0.94 MAPT (0.55) MAPTLMNAPOLBMEN1KMT2A
SCHEMBL25434651 0.94 MAPT (0.55) MAPTLMNAPOLBMEN1KMT2A
Hydrochloric Acid SCHEMBL25438946 0.93 MAPT (0.54) MAPTLMNAPOLBMEN1KMT2A
Hydrochloric Acid SCHEMBL25435613 0.93 MAPT (0.54) MAPTLMNAPOLBMEN1KMT2A
Hydrochloric Acid SCHEMBL25435609 0.93 MAPT (0.54) MAPTLMNAPOLBMEN1KMT2A
Trifluoroacetic Acid SCHEMBL31546415 0.90 MAPT (0.49) MAPTLMNAPOLBMEN1KMT2A
SCHEMBL25435779 0.84 MAPT (0.53) MAPTLMNAMEN1KMT2ASMN1; SMN2
SCHEMBL25435629 0.83 LMNA (0.61) MAPTLMNAPOLBMEN1KMT2A
Hydrochloric Acid SCHEMBL25439425 0.83 MAPT (0.53) MAPTLMNAMEN1KMT2ASMN1; SMN2
SCHEMBL25401737 0.83 LMNA (0.61) MAPTLMNAPOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 MAPT 2999/4885LMNA 1344/4885POLB 1664/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MAPT 2999/4885LMNA 1344/4885POLB 1664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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