Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
| ▸ | CLTC | Q00610 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | RGS4 | P49798 | 1/20 | 0.42 |
| ▸ | RGS8 | P57771 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31208038 | 1.00 | KDM4E (0.48) | KDM4EMAPTTP53RXFP1LMNA | |
| SCHEMBL25432242 | 0.86 | KDM4E (0.44) | KDM4EMAPTTP53RXFP1LMNA | |
| SCHEMBL25430713 | 0.85 | KDM4E (0.44) | KDM4EMAPTTP53RXFP1LMNA | |
| SCHEMBL25434185 | 0.83 | SLC5A1 (0.43) | KDM4EMAPTTP53RXFP1LMNA | |
| SCHEMBL30496099 | 0.83 | SLC5A1 (0.43) | KDM4EMAPTTP53RXFP1LMNA | |
| SCHEMBL31528433 | 0.81 | KDM4E (0.41) | KDM4EMAPTTP53RXFP1LMNA | |
| SCHEMBL31014731 | 0.81 | TDP1 (0.57) | KDM4EMAPTRXFP1P2RX4TDP1 | |
| SCHEMBL30496014 | 0.77 | CHRM1 (0.39) | KDM4EMAPTTP53RXFP1LMNA | |
| SCHEMBL25433053 | 0.77 | CHRM1 (0.39) | KDM4EMAPTTP53RXFP1LMNA | |
| SCHEMBL14743265 | 0.75 | CHRM5 (0.44) | KDM4EMAPTTP53LMNAP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025073554-A2 | PARP1 INHIBITOR COMPOUNDS | Duke Street Bio Limited (GB) | 2025-04-10 | — | — | WO | disclosed |
| EP-4444305-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |