Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25433053 | 1.00 | CHRM1 (0.39) | CHRM1SLC5A1SLC5A2KDM4EALDH1A1 | |
| SCHEMBL25430413 | 0.82 | SIGMAR1 (0.40) | SLC5A1SLC5A2CYP3A4SMN1; SMN2CYP2D6 | |
| SCHEMBL30496054 | 0.82 | SIGMAR1 (0.40) | SLC5A1SLC5A2CYP3A4SMN1; SMN2CYP2D6 | |
| SCHEMBL31208038 | 0.77 | KDM4E (0.48) | SLC5A1SLC5A2KDM4EALDH1A1RXFP1 | |
| SCHEMBL25433242 | 0.77 | KDM4E (0.48) | SLC5A1SLC5A2KDM4EALDH1A1RXFP1 | |
| SCHEMBL25432242 | 0.73 | KDM4E (0.44) | SLC5A1SLC5A2KDM4EALDH1A1RXFP1 | |
| SCHEMBL31208032 | 0.73 | P2RX3 (0.39) | MAPT | |
| SCHEMBL25430713 | 0.72 | KDM4E (0.44) | SLC5A1SLC5A2KDM4EALDH1A1RXFP1 | |
| SCHEMBL31528433 | 0.71 | KDM4E (0.41) | SLC5A1SLC5A2KDM4EALDH1A1RXFP1 | |
| SCHEMBL25434185 | 0.71 | SLC5A1 (0.43) | CHRM1SLC5A1SLC5A2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4674841-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2026-01-07 | — | — | EP | disclosed |
| CN-118973578-A | Pharmaceutical compounds | 杜克街生物有限公司 | 2024-11-15 | — | — | CN | disclosed |
| EP-4444305-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |