SCHEMBL25433682

SCHEMBL25433682

CC(C)=C(C)C(=O)OC[SiH3]

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CHRM5 P08912 2/20 0.31
CHRM1 P11229 2/20 0.31
CHRM3 P20309 2/20 0.31
PGR P06401 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
HTR1A P08908 1/20 0.31
CHRNB2 P17787 1/20 0.31
TBXA2R P21731 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA7 P36544 1/20 0.31
CHRNA4 P43681 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CHRNA10 Q9GZZ6 1/20 0.31
CHRNA9 Q9UGM1 1/20 0.31
GALR3 O60755 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL859744 0.76 ALDH1A1 (0.52) ALDH1A1LMNAHSD17B10SMN1; SMN2GAA
SCHEMBL15476097 0.76 ALDH1A1 (0.33) ALDH1A1LMNAHSD17B10CHRM5CHRM1
SCHEMBL25430791 0.75
SCHEMBL182508 0.74 LMNA (0.32) ALDH1A1LMNAHSD17B10CHRM5CHRM1
Ammonia Solution, Strong SCHEMBL3746512 0.74 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10SMN1; SMN2GAA
SCHEMBL15534156 0.73
SCHEMBL14409231 0.72 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10CHRM5CHRM1
SCHEMBL958243 0.72 TSHR (0.39) ALDH1A1LMNAHSD17B10CHRM5CHRM1
SCHEMBL16319973 0.72 ALDH1A1 (0.31) ALDH1A1LMNAHSD17B10CHRM5CHRM1
SCHEMBL129272 0.72 TSHR (0.42) ALDH1A1LMNAHSD17B10CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023148171-A1 MULTIFUNCTIONAL CROSSLINKING AGENTS AND OPHTHALMIC DEVICES FORMED THEREFROM BAUSCH + LOMB IRELAND LIMITED (IE) 2023-08-10 WO disclosed