1,4-Butanediol

1,4-Butanediol

SCHEMBL25433697

O=C(O)c1cocc1C(=O)O.OCCCCO

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.37
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
HTT P42858 1/20 0.37
LDHA P00338 1/20 0.35
CYP1A2 P05177 2/20 0.35
ALDH1A1 P00352 2/20 0.35
ALOX15 P16050 1/20 0.35
CAMK2A Q9UQM7 1/20 0.35
CA2 P00918 3/20 0.33
KDM4E B2RXH2 2/20 0.33
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
DHODH Q02127 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
HMGB1 P09429 1/20 0.30
HPGD P15428 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,3-Propanediol SCHEMBL28693826 0.95 HTT (0.37) GPR84FFAR1FFAR4HTTLDHA
Ethylene Glycol SCHEMBL25435561 0.90 LDHA (0.38) HTTLDHACYP1A2ALDH1A1ALOX15
SCHEMBL36897 0.84 ALDH1A1 (0.45) LDHACYP1A2ALDH1A1ALOX15CA2
Hydrochloric Acid SCHEMBL11203129 0.82 ALDH1A1 (0.43) LDHACYP1A2ALDH1A1ALOX15CA2
SCHEMBL11574505 0.82 ALDH1A1 (0.43) LDHACYP1A2ALDH1A1ALOX15CA2
Hydrochloric Acid SCHEMBL7231265 0.82 ALDH1A1 (0.43) LDHACYP1A2ALDH1A1ALOX15CA2
Butane SCHEMBL3012832 0.78 LDHA (0.37) LDHACYP1A2ALDH1A1ALOX15CA2
SCHEMBL5253316 0.76 LDHA (0.35) LDHACYP1A2ALDH1A1ALOX15CA2
Phthalic Acid SCHEMBL10360600 0.73 ALDH1A1 (0.70) HTTALDH1A1ALOX15CA2KDM4E
Phthalic Acid SCHEMBL5690459 0.73 ALDH1A1 (0.70) CYP1A2ALDH1A1ALOX15CA2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023173791-A1 POLYESTER MATERIAL AND POLYESTER PRODUCT, AND PREPARATION METHODS THEREFOR AND USE THEREOF 中国科学院宁波材料技术与工程研究所 2023-09-21 WO disclosed