Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10738039 | 1.00 | MEN1 (0.36) | MEN1ALDH1A1CYP3A4KMT2AGP6 | |
| SCHEMBL660760 | 0.86 | — | — | |
| SCHEMBL660761 | 0.86 | — | — | |
| SCHEMBL183432 | 0.74 | CA1 (0.34) | MEN1ALDH1A1KMT2ACYP19A1 | |
| SCHEMBL1681776 | 0.74 | LMNA (0.31) | MEN1ALDH1A1CYP3A4KMT2A | |
| SCHEMBL21575977 | 0.74 | CA1 (0.34) | MEN1ALDH1A1KMT2ACYP19A1 | |
| SCHEMBL9419571 | 0.74 | CA1 (0.34) | MEN1ALDH1A1KMT2ACYP19A1 | |
| SCHEMBL7149090 | 0.74 | LMNA (0.31) | MEN1ALDH1A1CYP3A4KMT2A | |
| SCHEMBL30198804 | 0.73 | MEN1 (0.33) | MEN1ALDH1A1CYP3A4KMT2A | |
| Acetone SCHEMBL28103893 | 0.72 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3736268-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS | Signal Pharmaceuticals, LLC (US) | 2020-11-11 | — | — | EP | disclosed |
| EP-3082819-B1 | SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARM LLC (US) | 2020-06-17 | — | — | EP | disclosed |
| US-9783505-B2 | Substituted diaminopyrimidyl compounds, compositions thereof, and methods of treatment therewith | SIGNAL PHARMACEUTICALS, LLC (US) | 2017-10-10 | — | — | US | disclosed |
| EP-3136461-A1 | PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL IN WHICH SAME IS USED, AND METHOD FOR MANUFACTURING PHOTOELECTRIC CONVERSION ELEMENT | Fujifilm Corporation (JP) | 2017-03-01 | — | — | EP | disclosed |
| US-20170040121-A1 | PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL USING THE SAME, AND METHOD FOR MANUFACTURING PHOTOELECTRIC CONVERSION ELEMENT | FUJIFILM CORPORATION (JP) | 2017-02-09 | — | — | US | disclosed |
| US-20170040121-A1 | PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL USING THE SAME, AND METHOD FOR MANUFACTURING PHOTOELECTRIC CONVERSION ELEMENT | FUJIFILM CORPORATION (JP) | 2017-02-09 | — | — | US | disclosed |
| US-9556126-B2 | Substituted diaminopyrimidyl compounds, compositions thereof, and methods of treatment therewith | SIGNAL PHARMACEUTICALS, LLC (US) | 2017-01-31 | — | — | US | disclosed |
| US-20160354374-A1 | SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARM LLC (US) | 2016-12-08 | — | — | US | disclosed |
| CN-106170290-A | Substituted di-amino-pyrimidine based compound, combinations thereof and treatment method thereof | 西格诺药品有限公司 | 2016-11-30 | — | — | CN | disclosed |
| EP-3082819-A1 | SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | Signal Pharmaceuticals, LLC (US) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015095679-A1 | SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARMACEUTICALS, LLC (US) | 2015-06-25 | — | — | WO | disclosed |
| EP-2194073-B1 | Positive-working photosensitive composition, method for pattern formation using the composition, resin for use in the composition, and monomer. | FUJIFILM CORP (JP) | 2013-06-05 | — | — | EP | disclosed |
| US-8043791-B2 | Positive photosensitive composition, pattern forming method using the composition and resin for use in the composition | FUJIFILM CORPORATION (JP) | 2011-10-25 | — | — | US | disclosed |
| US-8043791-B2 | Positive photosensitive composition, pattern forming method using the composition and resin for use in the composition | FUJIFILM CORPORATION (JP) | 2011-10-25 | — | — | US | disclosed |
| US-8043791-B2 | Positive photosensitive composition, pattern forming method using the composition and resin for use in the composition | FUJIFILM CORPORATION (JP) | 2011-10-25 | — | — | US | disclosed |
| US-20100216072-A1 | POSITIVE PHOTOSENSITIVE COMPOSITION, PATTERN FORMING METHOD USING THE COMPOSITION AND RESIN FOR USE IN THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2010-08-26 | — | — | US | disclosed |
| US-20100216072-A1 | POSITIVE PHOTOSENSITIVE COMPOSITION, PATTERN FORMING METHOD USING THE COMPOSITION AND RESIN FOR USE IN THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2010-08-26 | — | — | US | disclosed |
| US-20100216072-A1 | POSITIVE PHOTOSENSITIVE COMPOSITION, PATTERN FORMING METHOD USING THE COMPOSITION AND RESIN FOR USE IN THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2010-08-26 | — | — | US | disclosed |
| EP-2194073-A1 | POSITIVE-WORKING PHOTOSENSITIVE COMPOSITION, METHOD FOR PATTERN FORMATION USING THE COMPOSITION, AND RESIN FOR USE IN THE COMPOSITION | Fujifilm Corporation (JP) | 2010-06-09 | — | — | EP | disclosed |
| EP-2194073-A1 | POSITIVE-WORKING PHOTOSENSITIVE COMPOSITION, METHOD FOR PATTERN FORMATION USING THE COMPOSITION, AND RESIN FOR USE IN THE COMPOSITION | Fujifilm Corporation (JP) | 2010-06-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160354374-A1 | SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | PRKCQ, PRKCH, PRKCE | MEN1 3777/4885ALDH1A1 3945/4885CYP3A4 3956/4885 |
| US-20100216072-A1 | POSITIVE PHOTOSENSITIVE COMPOSITION, PATTERN FORMING METHOD USING THE COMPOSITION AND RESIN FOR USE IN THE COMPOSITION | LCP1, SUN2, EEF1D | MEN1 3629/4885ALDH1A1 4655/4885CYP3A4 3661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.