Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | EEF2K | O00418 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25435598 | 1.00 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL31529481 | 0.91 | PIK3CA (0.40) | SCN1ASCN5ASCN8AALOX5APFEN1 | |
| SCHEMBL25437180 | 0.91 | PIK3CA (0.40) | SCN1ASCN5ASCN8AALOX5APFEN1 | |
| SCHEMBL31529527 | 0.86 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL25706240 | 0.83 | CA1 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2ATDP1 | |
| SCHEMBL31529538 | 0.79 | TEAD1 (0.34) | ALDH1A1EEF2KS1PR1PDE2AL3MBTL1 | |
| SCHEMBL25436309 | 0.78 | MAPT (0.37) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL25436312 | 0.78 | MAPT (0.37) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL30438540 | 0.78 | SCN1A (0.35) | ALDH1A1SMN1; SMN2SCN1ASCN5ASCN8A | |
| SCHEMBL25703348 | 0.78 | SCN1A (0.35) | ALDH1A1SMN1; SMN2SCN1ASCN5ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094830-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | LARIO THERAPEUTICS LIMITED (GB) | 2023-06-01 | — | — | WO | disclosed |