Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | MTOR | P42345 | 3/20 | 0.34 |
| ▸ | CLK1 | P49759 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.33 |
| ▸ | FEN1 | P39748 | 5/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25703348 | 1.00 | SCN1A (0.35) | SCN1ASCN5ASCN8APIK3CAMTOR | |
| SCHEMBL30438495 | 0.92 | PIK3CA (0.41) | SCN1ASCN5ASCN8APIK3CAMTOR | |
| SCHEMBL25701931 | 0.92 | PIK3CA (0.41) | SCN1ASCN5ASCN8APIK3CAMTOR | |
| SCHEMBL31529527 | 0.91 | ALDH1A1 (0.37) | SCN1ASCN5ASCN8APIK3CAMTOR | |
| SCHEMBL25437180 | 0.78 | PIK3CA (0.40) | SCN1ASCN5ASCN8APIK3CAMTOR | |
| SCHEMBL31529481 | 0.78 | PIK3CA (0.40) | SCN1ASCN5ASCN8APIK3CAMTOR | |
| SCHEMBL25435602 | 0.78 | ALDH1A1 (0.37) | SCN1ASCN5ASCN8APIK3CAALDH1A1 | |
| SCHEMBL25435598 | 0.78 | ALDH1A1 (0.37) | SCN1ASCN5ASCN8APIK3CAALDH1A1 | |
| SCHEMBL31529561 | 0.77 | BRAF (0.35) | SCN1ASCN5ASCN8AALDH1A1ALOX5AP | |
| SCHEMBL30438630 | 0.77 | BRAF (0.35) | SCN1ASCN5ASCN8AALDH1A1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4436955-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | Lario Therapeutics Limited (GB) | 2024-10-02 | — | — | EP | disclosed |
| WO-2023094830-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | LARIO THERAPEUTICS LIMITED (GB) | 2023-06-01 | — | — | WO | disclosed |