Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5578474 | 0.88 | SMN1; SMN2 (0.51) | ALDH1A1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL30413328 | 0.84 | CYP3A4 (0.40) | OXTRTSHRALDH1A1KMT2ACYP2D6 | |
| SCHEMBL38333 | 0.84 | CYP2C9 (0.46) | TSHRALDH1A1KMT2ACYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL7012082 | 0.83 | CYP2C9 (0.44) | TSHRALDH1A1KMT2ACYP2D6MEN1 | |
| SCHEMBL7013380 | 0.80 | TNKS (0.46) | ALDH1A1KMT2ACYP2D6MEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL7006808 | 0.79 | TNKS (0.43) | ALDH1A1TNKSTNKS2POLBCCR5 | |
| Hydrochloric Acid SCHEMBL7006198 | 0.79 | TNKS (0.45) | ALDH1A1KMT2ACYP2D6MEN1MAPK1 | |
| SCHEMBL30412930 | 0.73 | TSHR (0.51) | TSHRALDH1A1KMT2ATNKSTNKS2 | |
| SCHEMBL1670650 | 0.73 | TNKS (0.46) | TNKSTNKS2CCR5 | |
| Hydrochloric Acid SCHEMBL25230408 | 0.72 | TNKS (0.45) | TNKSTNKS2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192957-A2 | TRPML MODULATORS | Casma Therapeutics, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032073-A2 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2022-02-10 | — | — | WO | disclosed |