Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NEK2 | P51955 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7006808 | 0.85 | TNKS (0.43) | ALDH1A1POLBTNKSTNKS2MAPT | |
| SCHEMBL7013380 | 0.81 | TNKS (0.46) | KMT2AALDH1A1TNKSTNKS2 | |
| Hydrochloric Acid SCHEMBL7006198 | 0.80 | TNKS (0.45) | KMT2AALDH1A1TNKSTNKS2 | |
| SCHEMBL38333 | 0.80 | CYP2C9 (0.46) | TSHRHPGDKMT2AALDH1A1CYP2C19 | |
| Hydrochloric Acid SCHEMBL7012082 | 0.79 | CYP2C9 (0.44) | TSHRHPGDKMT2AALDH1A1CYP2C19 | |
| SCHEMBL6422849 | 0.77 | SIGMAR1 (0.57) | TSHRKMT2AALDH1A1GAACYP2C19 | |
| SCHEMBL735675 | 0.73 | TSHR (0.81) | TSHRHPGDKMT2ARAB9ANPC1 | |
| SCHEMBL25436735 | 0.73 | OXTR (0.44) | TSHRHPGDKMT2ANEK2ALDH1A1 | |
| SCHEMBL5578474 | 0.73 | SMN1; SMN2 (0.51) | KMT2ANEK2ALDH1A1GAAPOLB | |
| SCHEMBL1222990 | 0.72 | AVPR1A (0.54) | KMT2ATNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116113698-A | TRPML modulators | 卡斯玛治疗公司 | 2023-05-12 | — | — | CN | disclosed |