Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 5/20 | 0.56 |
| ▸ | TDP2 | O95551 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30428318 | 0.87 | ALDH1A1 (0.59) | ASIC3DRD2DRD3ALDH1A1F2 | |
| SCHEMBL1026101 | 0.87 | ALDH1A1 (0.59) | ASIC3DRD2DRD3ALDH1A1F2 | |
| SCHEMBL1020108 | 0.86 | ASIC3 (0.55) | ASIC3SLC2A1CD274SYK | |
| SCHEMBL3707604 | 0.86 | ASIC3 (0.55) | ASIC3SLC2A1DRD2DRD3F2 | |
| Hydrochloric Acid SCHEMBL22654009 | 0.85 | ALDH1A1 (0.58) | ASIC3SLC2A1DRD2DRD3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28278640 | 0.84 | ALDH1A1 (0.56) | ASIC3SLC2A1DRD2DRD3ALDH1A1 | |
| SCHEMBL6347388 | 0.82 | ASIC3 (0.65) | ASIC3DRD2DRD3CD274 | |
| SCHEMBL29589725 | 0.80 | ALDH1A1 (0.59) | DRD2DRD3ALDH1A1 | |
| SCHEMBL1026913 | 0.80 | ALDH1A1 (0.59) | DRD2DRD3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15671006 | 0.79 | ALDH1A1 (0.58) | SLC2A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109912-A1 | 3, 4-DIHYDROISOQUINOLIN-1 (2H) -ONES DERIVATIVES AS STING ANTAGONISTS AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2023-06-22 | — | — | WO | disclosed |