Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 4/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.43 |
| ▸ | PARP1 | P09874 | 5/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 3/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30406053 | 1.00 | KIT (0.51) | KITNAMPTGPR119PDGFRBPDGFRA | |
| SCHEMBL30455937 | 0.91 | KIT (0.49) | KITPDGFRBPARP1CYP11B2TNKS | |
| SCHEMBL25225988 | 0.91 | KIT (0.49) | KITPDGFRBPARP1CYP11B2TNKS | |
| SCHEMBL31027420 | 0.90 | KIT (0.44) | KITNAMPTGPR119PDGFRBPARP1 | |
| SCHEMBL25275689 | 0.87 | PDGFRB (0.43) | KITPDGFRBPDGFRAMEN1ALDH1A1 | |
| SCHEMBL30405196 | 0.87 | PDGFRB (0.41) | KITPDGFRBPDGFRAMEN1ALDH1A1 | |
| SCHEMBL25276663 | 0.86 | KIT (0.45) | KITPARP1CYP11B2TNKSTNKS2 | |
| SCHEMBL25280892 | 0.83 | KIT (0.44) | KITGPR119PARP1CYP11B2TNKS | |
| SCHEMBL30405237 | 0.83 | KIT (0.44) | KITGPR119PARP1CYP11B2TNKS | |
| SCHEMBL25224723 | 0.83 | KIT (0.41) | KITPDGFRBPARP1CYP11B2TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |