Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 4/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 5/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25229702 | 0.91 | AKT1 (0.44) | PDGFRBPDGFRAAKT1JAK3KIT | |
| SCHEMBL25234444 | 0.89 | PDGFRB (0.41) | PDGFRBCYP1A2CYP3A4ALDH1A1CYP2D6 | |
| SCHEMBL30406267 | 0.89 | PDGFRB (0.41) | PDGFRBCYP1A2CYP3A4ALDH1A1CYP2D6 | |
| SCHEMBL25437390 | 0.87 | KIT (0.51) | PDGFRBPDGFRACYP1A2CYP3A4MEN1 | |
| SCHEMBL30406053 | 0.87 | KIT (0.51) | PDGFRBPDGFRACYP1A2CYP3A4MEN1 | |
| SCHEMBL30405196 | 0.85 | PDGFRB (0.41) | PDGFRBPDGFRACYP1A2CYP3A4MEN1 | |
| SCHEMBL25725210 | 0.84 | CYP1A2 (0.41) | PDGFRBPDGFRACYP1A2CYP3A4KDM4E | |
| SCHEMBL31027439 | 0.84 | CYP1A2 (0.51) | PDGFRBPDGFRACYP1A2CYP3A4KDM4E | |
| SCHEMBL31501681 | 0.84 | CYP1A2 (0.51) | PDGFRBPDGFRACYP1A2CYP3A4KDM4E | |
| SCHEMBL25276551 | 0.84 | CYP1A2 (0.51) | PDGFRBPDGFRACYP1A2CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |