Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 6/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.38 |
| ▸ | ATXN2 | Q99700 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 3/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30405888 | 0.91 | PDGFRB (0.41) | PDGFRBPDGFRAOPRD1OPRK1ENPP2 | |
| SCHEMBL25437390 | 0.87 | KIT (0.51) | PDGFRBPDGFRAMEN1KMT2AALDH1A1 | |
| SCHEMBL30406053 | 0.87 | KIT (0.51) | PDGFRBPDGFRAMEN1KMT2AALDH1A1 | |
| SCHEMBL25275689 | 0.85 | PDGFRB (0.43) | PDGFRBPDGFRAMEN1KMT2AALDH1A1 | |
| SCHEMBL30405875 | 0.85 | PDGFRB (0.39) | PDGFRBPDGFRAOPRD1OPRK1ENPP2 | |
| SCHEMBL30405747 | 0.82 | HTT (0.48) | PDGFRBPDGFRAOPRD1OPRK1ENPP2 | |
| SCHEMBL30405798 | 0.80 | OPRD1 (0.43) | PDGFRBOPRD1OPRK1ENPP2ATXN2 | |
| SCHEMBL30406045 | 0.79 | MAPK7 (0.44) | ENPP2ATXN2KITMTNR1B | |
| SCHEMBL30406110 | 0.78 | HSD17B10 (0.44) | OPRD1OPRK1MAPTALDH1A1LMNA | |
| SCHEMBL30405783 | 0.78 | MTNR1B (0.42) | PDGFRBPDGFRAOPRD1OPRK1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444300-A2 | INHIBITORS OF MENIN-MLL INTERACTION | Bala Therapeutics, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |