Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.40 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.40 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14347555 | 0.84 | NPC1 (0.41) | CNR1SMN1; SMN2PPARGPPARAALDH1A1 | |
| SCHEMBL16501745 | 0.84 | NPC1 (0.41) | CNR1SMN1; SMN2PPARGPPARAALDH1A1 | |
| SCHEMBL22427640 | 0.80 | L3MBTL1 (0.50) | NPSR1NPC1RAB9AMAPT | |
| SCHEMBL18422575 | 0.77 | LMNA (0.50) | CNR1SMN1; SMN2PPARGPPARAALDH1A1 | |
| SCHEMBL25436650 | 0.76 | PPARG (0.40) | CNR1SMN1; SMN2PPARGPPARAALDH1A1 | |
| SCHEMBL2152925 | 0.75 | TNF (0.50) | SMN1; SMN2PPARGPPARAALDH1A1NPC1 | |
| SCHEMBL6377776 | 0.75 | TNF (0.50) | SMN1; SMN2PPARGPPARAALDH1A1NPC1 | |
| SCHEMBL27479477 | 0.75 | TNF (0.50) | SMN1; SMN2PPARGPPARAALDH1A1NPC1 | |
| SCHEMBL20272568 | 0.74 | PPARG (0.49) | SMN1; SMN2PPARGPPARAALDH1A1NPC1 | |
| SCHEMBL31370388 | 0.74 | PPARG (0.49) | SMN1; SMN2PPARGPPARAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107597-A2 | BICYCLIC HETEROAROMATIC AMIDE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |