SCHEMBL2543874

SCHEMBL2543874

Cc1ccccc1C(O)CO

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.46
KDM4E B2RXH2 1/20 0.44
CYP1A2 P05177 1/20 0.44
GAA P10253 1/20 0.42
ACP3 P15309 1/20 0.40
TSHR P16473 2/20 0.39
ACHE P22303 1/20 0.39
SLC6A2 P23975 3/20 0.38
SLC6A4 P31645 3/20 0.38
CYP2D6 P10635 3/20 0.38
CYP3A4 P08684 2/20 0.38
SLC6A3 Q01959 2/20 0.38
KCNH2 Q12809 2/20 0.38
LMNA P02545 1/20 0.37
GABRA1 P14867 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
AOC3 Q16853 1/20 0.35
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31376576 1.00 ESR1 (0.46) ESR1KDM4ECYP1A2GAAACP3
SCHEMBL6481460 1.00 ESR1 (0.46) ESR1KDM4ECYP1A2GAAACP3
SCHEMBL17660054 1.00 ESR1 (0.46) ESR1KDM4ECYP1A2GAAACP3
SCHEMBL1549219 0.83 LMNA (0.39) KDM4ETSHRCYP2D6LMNAGABRA1
SCHEMBL5265776 0.83 ESR1 (0.43) ESR1KDM4ECYP1A2GAAACP3
SCHEMBL3929484 0.82 LMNA (0.52) ESR1KDM4ECYP1A2GAAACP3
SCHEMBL29359681 0.82 ESR1 (0.46) ESR1KDM4EGAAACP3TSHR
SCHEMBL593087 0.82 LMNA (0.52) ESR1KDM4ECYP1A2GAAACP3
SCHEMBL22445613 0.82 ESR1 (0.46) ESR1KDM4EGAAACP3TSHR
SCHEMBL7153630 0.82 ESR1 (0.46) ESR1KDM4EGAAACP3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118119655-A Method for preparing melt-processible cellulose ester compositions comprising amorphous biofilm 伊士曼化工公司 2024-05-31 CN claimed
CN-118076680-A Melt-processible cellulose ester compositions comprising amorphous biofilm 伊士曼化工公司 2024-05-24 CN claimed
CN-118076679-A Articles containing melt-processible cellulose ester compositions comprising amorphous biofilm 伊士曼化工公司 2024-05-24 CN claimed
CN-118076683-A Articles comprising melt-processible cellulose acetate compositions containing amorphous biological fillers 伊士曼化工公司 2024-05-24 CN claimed
CN-118076681-A Process for preparing melt-processible cellulose ester compositions comprising basic filler 伊士曼化工公司 2024-05-24 CN claimed
CN-118076678-A Articles containing melt-processible cellulose ester compositions comprising basic filler 伊士曼化工公司 2024-05-24 CN claimed
CN-118076682-A Melt-processible cellulose ester compositions comprising basic filler 伊士曼化工公司 2024-05-24 CN claimed
CN-118119655-A Method for preparing melt-processible cellulose ester compositions comprising amorphous biofilm 伊士曼化工公司 2024-05-31 CN disclosed
CN-118076679-A Articles containing melt-processible cellulose ester compositions comprising amorphous biofilm 伊士曼化工公司 2024-05-24 CN disclosed
CN-118076678-A Articles containing melt-processible cellulose ester compositions comprising basic filler 伊士曼化工公司 2024-05-24 CN disclosed
CN-118076683-A Articles comprising melt-processible cellulose acetate compositions containing amorphous biological fillers 伊士曼化工公司 2024-05-24 CN disclosed
CN-118076681-A Process for preparing melt-processible cellulose ester compositions comprising basic filler 伊士曼化工公司 2024-05-24 CN disclosed
CN-118076680-A Melt-processible cellulose ester compositions comprising amorphous biofilm 伊士曼化工公司 2024-05-24 CN disclosed
CN-102131548-B Air-supply system for breathing SK ENERGY CO LTD 2013-04-24 CN disclosed
US-20110259198-A1 AIR-SUPPLY SYSTEM FOR BREATHING SK INNOVATION CO., LTD. (KR) 2011-10-27 US disclosed
CN-102131548-A Air-supply system for breathing SU KIM BUM 2011-07-20 CN disclosed
US-20090203667-A1 PENTADIENAMIDE DERIVATIVES KYOWA HAKKO KIRIN CO., LTD. (JP) 2009-08-13 US disclosed
US-20090203667-A1 PENTADIENAMIDE DERIVATIVES KYOWA HAKKO KIRIN CO., LTD. (JP) 2009-08-13 US disclosed
EP-2050734-A1 PENTADIENAMIDE DERIVATIVE Kyowa Hakko Kirin Co., Ltd. (JP) 2009-04-22 EP disclosed
US-5244879-A 23-nor-23-oxa avermectin analogs are active anthelmintic agents MERCK & CO., INC. (US) 1993-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203667-A1 PENTADIENAMIDE DERIVATIVES PRMT1, REN, NGLY1 ESR1 2873/4885KDM4E 212/4885CYP1A2 1186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.