Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25438827 | 1.00 | SMN1; SMN2 (0.62) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL25438820 | 1.00 | SMN1; SMN2 (0.62) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL25439272 | 0.91 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL25439275 | 0.91 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL25433025 | 0.90 | MEN1 (0.67) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL25433029 | 0.90 | MEN1 (0.67) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL30584814 | 0.90 | SMN1; SMN2 (0.61) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL26306535 | 0.90 | SMN1; SMN2 (0.61) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL30585037 | 0.90 | SMN1; SMN2 (0.61) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL30584800 | 0.89 | SMN1; SMN2 (0.60) | SMN1; SMN2MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177700-A2 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2023-09-21 | — | — | WO | disclosed |