Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAT2A | P31153 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30421525 | 1.00 | PTPN11 (0.54) | PTPN11MAPTMAT2AMEN1TSHR | |
| SCHEMBL25439758 | 0.90 | PTPN11 (0.48) | PTPN11MAPTMAT2AIRAK4POLB | |
| SCHEMBL25214352 | 0.86 | PTPN11 (0.51) | PTPN11MAPTMEN1TSHRKMT2A | |
| SCHEMBL30423069 | 0.85 | PTPN11 (0.50) | PTPN11MAPTMEN1TSHRKMT2A | |
| SCHEMBL25438924 | 0.85 | PTPN11 (0.50) | PTPN11MAPTMEN1TSHRKMT2A | |
| SCHEMBL31485521 | 0.85 | MAT2A (0.47) | PTPN11MAPTMAT2APOLBNOTUM | |
| SCHEMBL30422948 | 0.85 | MAT2A (0.43) | PTPN11MAPTMAT2ATP53IRAK4 | |
| Hydrochloric Acid SCHEMBL30422152 | 0.85 | MAT2A (0.47) | PTPN11MAPTMAT2APOLBNOTUM | |
| Hydrochloric Acid SCHEMBL25213549 | 0.85 | MAT2A (0.47) | PTPN11MAPTMAT2APOLBNOTUM | |
| SCHEMBL30422586 | 0.84 | MAT2A (0.42) | PTPN11MAPTMAT2AIRAK4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102231-A1 | 5-PYRIMIDINECARBOXAMIDE DERIVATIVES AND METHODS OF USING THE SAME | RGENTA THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | WO | disclosed |