Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10337645 | 0.59 | BCL2L1 (0.55) | NPC1RAB9ASMN1; SMN2POLBLPL | |
| SCHEMBL12562793 | 0.59 | BCL2L1 (0.55) | NPC1RAB9ASMN1; SMN2POLBLPL | |
| SCHEMBL26821699 | 0.59 | BCL2L1 (0.55) | NPC1RAB9ASMN1; SMN2POLBLPL | |
| SCHEMBL197346 | 0.59 | BCL2L1 (0.55) | NPC1RAB9ASMN1; SMN2POLBLPL | |
| SCHEMBL10300262 | 0.59 | BCL2L1 (0.55) | NPC1RAB9ASMN1; SMN2POLBLPL | |
| SCHEMBL9812881 | 0.57 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2TSHRPTGS1 | |
| SCHEMBL28060792 | 0.57 | BCL2L1 (0.52) | NPC1RAB9ASMN1; SMN2POLBLPL | |
| SCHEMBL2289115 | 0.54 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2TSHRTP53 | |
| SCHEMBL20804472 | 0.54 | ACHE (0.81) | NPC1RAB9ASMN1; SMN2PTGS1LMNA | |
| Methylamine SCHEMBL27499302 | 0.53 | ACHE (0.60) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555100-B1 | BENZODIAZEPINE DERIVATIVES, COMPOSITIONS, AND METHODS FOR TREATING COGNITIVE IMPAIRMENT | AGENEBIO INC (US) | 2023-05-10 | — | — | EP | disclosed |